Research Techinican - Cancer Center - Part-time

Site: The General Hospital Corporationp style="text-align:inherit"br / /pp style="text-align:left"At Mass General Brigham, we know it takes a surprising range of talented professionals to advance our mission—from doctors, nurses, business people and tech experts, to dedicated researchers and systems analysts. As a not-for-profit organization, Mass General Brigham is committed to supporting patient care, research, teaching, and service to the community. We place great value on being a diverse, equitable and inclusive organization as we aim to reflect the diversity of the patients we serve./pp style="text-align:inherit"/pp style="text-align:left"At Mass General Brigham, we believe a diverse set of backgrounds and lived experiences makes us stronger by challenging our assumptions with new perspectives that can drive revolutionary discoveries in medical innovations in research and patient care. Therefore, we invite and welcome applicants from traditionally underrepresented groups in healthcare — people of color, people with disabilities, LGBTQ community, and/or gender expansive, first and second-generation immigrants, veterans, and people from different socioeconomic backgrounds – to apply./pp style="text-align:inherit"br / /pp style="text-align:inherit"br / /pp style="text-align:left"ubJob Summary/b/u/pThe Corcoran lab seeks a highly motivated individual with a strong interest in pursuing a future academic career in science or medicine. This is an ideal position for a recent graduate who wants to gain an intense research experience before pursuing graduate or medical school. The candidate will take responsibility in basic science and translational research projects under close supervision of post-doctoral research fellows in the lab, as well as Dr. Ryan Corcoran (PI). Our current technicians have various roles within the lab. You will be introduced and trained on techniques used in the lab, depending on the departmental need. The current position available in the lab works mainly in the animal (mouse) facility with postdocs currently working on animal experiments, but the candidate will also have the opportunity to take part in other projects in the main lab.p style="text-align:inherit"br / /pdivdivdivdivdivdivdivp style="text-align:left"ubQualifications/b/u/p/div/div/div/div/div/div/divpThe Corcoran lab is involved in investigating new and effective therapies for gastrointestinal cancers, mainly colorectal,/pppancreatic and liver cancers. Our group is interested in elucidating novel mechanisms of resistance to targeted cancer/pptherapeutics such as kinase inhibitors or immune checkpoint inhibitors (Ryan MB et al. Cell Reports 2022, Tian J et al./ppNature Medicine 2023, Fece de la Cruz F et al. Cancer Discovery 2024, Tanaka N et al. Cancer Discovery 2024)./pulliTissue culture techniques: maintenance of mouse/human cell lines in culture, cryopreservation, drug treatments,/liliplasmid transfections, lentiviral transduction./liliEstablish xenograft models, in vivo drug treatments, tumor isolation and processing for IHC./liliPerform standard molecular biology techniques (Western blotting, PCR, cloning, site-directed mutagenesis, CRISPR)./liliInterpretation of experimental results./liliInterest on establishing new and optimizing existing techniques in the lab./liliGeneration and maintenance of organoid cultures from patient biopsies./li/ulp style="text-align:inherit"br / /pdivdivdivdivdivdivdivp style="text-align:left"ubAdditional Job Details (if applicable)/b/u/p/div/div/div/div/div/div/divp style="text-align:inherit"br / /pdivdivdivdivdivdivdivp style="text-align:left"ubRemote Type/b/u/p/div/div/div/div/div/div/divOnsitep style="text-align:inherit"br / /pdivdivdivdivdivdivdivp style="text-align:left"ubWork Location/b/u/p/div/div/div/div/div/div/div149 Thirteenth Street Building 149p style="text-align:inherit"br / /pdivdivdivdivdivdivdivp style="text-align:left"ubScheduled Weekly Hours/b/u/p/div/div/div/div/div/div/div0p style="text-align:inherit"br / /pdivdivdivdivdivdivdivp style="text-align:left"ubEmployee Type/b/u/p/div/div/div/div/div/div/divPer Diemp style="text-align:inherit"br / /pdivdivdivdivdivdivdivp style="text-align:left"ubWork Shift/b/u/p/div/div/div/div/div/div/divDay (United States of America)p style="text-align:inherit"br / /pdivdivdivdivdivdivdivp style="text-align:left"ubEEO Statement:/b/u/p/div/div/div/div/div/div/divThe General Hospital Corporation is an Affirmative Action Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.p style="text-align:inherit"br / /pp style="text-align:left"ubMass General Brigham Competency Framework/b/u/pp style="text-align:left"At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline./p
Site: The General Hospital Corporationp style="text-align:inherit"br / /pp style="text-align:left"At Mass General Brigham, we know it takes a surprising range of talented professionals to advance our mission—from doctors, nurses, business people and tech experts, to dedicated researchers and systems analysts. As a not-for-profit organization, Mass General Brigham is committed to supporting patient care, research, teaching, and service to the community. We place great value on being a diverse, equitable and inclusive organization as we aim to reflect the diversity of the patients we serve./pp style="text-align:inherit"/pp style="text-align:left"At Mass General Brigham, we believe a diverse set of backgrounds and lived experiences makes us stronger by challenging our assumptions with new perspectives that can drive revolutionary discoveries in medical innovations in research and patient care. Therefore, we invite and welcome applicants from traditionally underrepresented groups in healthcare — people of color, people with disabilities, LGBTQ community, and/or gender expansive, first and second-generation immigrants, veterans, and people from different socioeconomic backgrounds – to apply./pp style="text-align:inherit"br / /pp style="text-align:inherit"br / /pp style="text-align:left"ubJob Summary/b/u/pThe Corcoran lab seeks a highly motivated individual with a strong interest in pursuing a future academic career in science or medicine. This is an ideal position for a recent graduate who wants to gain an intense research experience before pursuing graduate or medical school. The candidate will take responsibility in basic science and translational research projects under close supervision of post-doctoral research fellows in the lab, as well as Dr. Ryan Corcoran (PI). Our current technicians have various roles within the lab. You will be introduced and trained on techniques used in the lab, depending on the departmental need. The current position available in the lab works mainly in the animal (mouse) facility with postdocs currently working on animal experiments, but the candidate will also have the opportunity to take part in other projects in the main lab.p style="text-align:inherit"br / /pdivdivdivdivdivdivdivp style="text-align:left"ubQualifications/b/u/p/div/div/div/div/div/div/divpThe Corcoran lab is involved in investigating new and effective therapies for gastrointestinal cancers, mainly colorectal,/pppancreatic and liver cancers. Our group is interested in elucidating novel mechanisms of resistance to targeted cancer/pptherapeutics such as kinase inhibitors or immune checkpoint inhibitors (Ryan MB et al. Cell Reports 2022, Tian J et al./ppNature Medicine 2023, Fece de la Cruz F et al. Cancer Discovery 2024, Tanaka N et al. Cancer Discovery 2024)./pulliTissue culture techniques: maintenance of mouse/human cell lines in culture, cryopreservation, drug treatments,/liliplasmid transfections, lentiviral transduction./liliEstablish xenograft models, in vivo drug treatments, tumor isolation and processing for IHC./liliPerform standard molecular biology techniques (Western blotting, PCR, cloning, site-directed mutagenesis, CRISPR)./liliInterpretation of experimental results./liliInterest on establishing new and optimizing existing techniques in the lab./liliGeneration and maintenance of organoid cultures from patient biopsies./li/ulp style="text-align:inherit"br / /pdivdivdivdivdivdivdivp style="text-align:left"ubAdditional Job Details (if applicable)/b/u/p/div/div/div/div/div/div/divp style="text-align:inherit"br / /pdivdivdivdivdivdivdivp style="text-align:left"ubRemote Type/b/u/p/div/div/div/div/div/div/divOnsitep style="text-align:inherit"br / /pdivdivdivdivdivdivdivp style="text-align:left"ubWork Location/b/u/p/div/div/div/div/div/div/div149 Thirteenth Street Building 149p style="text-align:inherit"br / /pdivdivdivdivdivdivdivp style="text-align:left"ubScheduled Weekly Hours/b/u/p/div/div/div/div/div/div/div0p style="text-align:inherit"br / /pdivdivdivdivdivdivdivp style="text-align:left"ubEmployee Type/b/u/p/div/div/div/div/div/div/divPer Diemp style="text-align:inherit"br / /pdivdivdivdivdivdivdivp style="text-align:left"ubWork Shift/b/u/p/div/div/div/div/div/div/divDay (United States of America)p style="text-align:inherit"br / /pdivdivdivdivdivdivdivp style="text-align:left"ubEEO Statement:/b/u/p/div/div/div/div/div/div/divThe General Hospital Corporation is an Affirmative Action Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.p style="text-align:inherit"br / /pp style="text-align:left"ubMass General Brigham Competency Framework/b/u/pp style="text-align:left"At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline./p